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Joints may feel as if they hurt, but in reality FMS is a syndrome that affects the connective tissues that surround the joint, making it seem as if the joints themselves are hurting. (Of course, many fibromites also have arthritis - in which case the joints really do hurt as well.) This isn't surprising, as it has recently been found that the main problem in FMS is probably an aberration of the central pain mechanism, which involves neuroendocrine and immune dysfunctions.